Wijz. Tabaks- en rookwarenregeling ivm verbod op kenmerkende aroma's voor verhitte tabaksproducten

Reactie

Vraag1

Menthol and related cooling agents may mask the airway irritation caused by tobacco smoke, but the opposite is true for nicotine-containing aerosols from e-cigarettes. Activation of TRPM8 receptors enhances the perceived airway irritation produced by inhalation of e-liquids [1]. A mouse study also showed that menthol does not increase the airway irritation caused by nicotine inhalation [2]. These results confirm the experience of users who prefer menthol-containing e-liquids to increase the desired airway sensation (throat hit) caused by inhaling propylene glycol and nicotine. Taken together, published data and users' experience demonstrate that it can be excluded TRPM8 agonists will increase the likelihood of nicotine addiction in adolescents by facilitating the inhalation of nicotine-containing e-liquids.

Menthol and other cooling agents significantly contribute to smokers' successful and sustained switch to vaping. Based on a study on the influence of e-cigarette flavorings on the vaping and smoking behaviors of cigarette smokers, Litt and coworkers noted [3]: "Menthol-flavoured e-cigarettes were the most successful at suppressing cigarette use." In a recent study, Yoonseo et al. arrived at a similar conclusion [4]: "E-cigarette use is positively associated with both making smoking quit attempts and quit success. Those using flavored e-cigarettes, particularly menthol or mint, are more likely to quit successfully." Therefore, a ban on menthol or related cooling agents would significantly reduce the quit rates of smokers and threaten public health in the Netherlands.

1. Rosbrook, K. & Green, B. G. Sensory effects of menthol and nicotine in an e-cigarette. Nicotine Tob. Res. 18, 1588-1595 (2016)
2. Ni, F., Ogura, T. & Lin, W. Electronic cigarette liquid constituents induce nasal and tracheal sensory irritation in mice in regionally dependent fashion. Nicotine Tob. Res. 22, S35-S44 (2020)
3. Litt, M. D., Duffy, V. & Oncken, C. Cigarette smoking and electronic cigarette vaping patterns as a function of e-cigarette flavourings. Tob. Control 25 (Suppl. 2), ii67–ii72 (2016)
4. Mok, Y., Jeon, J., Levy, D. T. & Meza, R. Associations between e-cigarette use and e-cigarette flavors with cigarette smoking quit attempts and quit success: Evidence from a US Large, Nationally Representative 2018-2019 Survey. Nicotine & Tobacco Research 25, 541-552 (2023)